Super-resolution imaging
Blood flow imaging for atherosclerosis research
Atherosclerosis is a condition in which the blood vessels become narrowed or blocked due to the build-up of plaque, which is a mixture of fatty substances, cholesterol, and other materials. Wall shear stress (WSS) is the force exerted by blood flow on the inner surface of blood vessels. There is evidence to suggest that WSS plays a role in the development and progression of atherosclerosis. uPIV can not only provide detailed information about the flow patterns in the blood vessels, including the direction and velocity of blood flow but it can also be used to identify areas of low or high WSS. We have demonstrated the use of uPIV to measure wall shear stress accurately with and without the use of contrast agents both in 2D and in 3D.
Ultrasound